Designing Clinical Research 4e IE

Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in every chapter, with new material on: * non-inferiority trials for comparative effectiveness research * incidence-density case-control studies * confounding and effect modification * diagnostic test studies to inform prediction rules * ethical aspects of whole genome sequencing * automated data management approaches * new NIH grant-writing requirements Color format, and Electronic access, powered by Inkling (TM) as a free companion to the text * viewable through your browser or as a download to tablet or smartphone * the complete text with optimized navigation * note-sharing, highlighting and bookmarking capability * cross-linking of references and content * rapid search options linked to the new glossary