This book addresses the latest approaches to holistic Cyber-Physical System (CPS) resilience in real-world industrial applications. Ensuring the resilience of CPSs requires cross-discipline analysis and involves many challenges and open issues, including how to address evolving cyber-security threats. The book describes emerging paradigms and techniques from two main viewpoints: CPSs' exposure to new threats, and CPSs' potential to counteract them. Further, the chapters address topics ranging from risk modeling to threat management and mitigation. The book offers a clearly structured, highly accessible resource for a diverse readership, including graduate students, researchers and industry practitioners who are interested in evaluating and ensuring the resilience of CPSs in both the development and assessment stages. Foreword by Prof. Shiyan Hu, Chair of Cyber-Physical Systems at Linnaeus University, Sweden.