‏441.00 ₪

Industrial Microbiology

‏441.00 ₪

ISBN13

9783527340354

יצא לאור ב

Weinheim

זמן אספקה

21 ימי עסקים

עמודים

424

פורמט

Paperback / softback

תאריך יציאה לאור

13 בנוב׳ 2019

לדלג לסוף של גלריית תמונות

לדלג להתחלה של גלריית תמונות

פרטים

Focusing on current and future uses of microbes as production organisms, this practice-oriented textbook complements traditional texts on microbiology and biotechnology. The editors have brought together leading researchers and professionals from the entire field of industrial microbiology and together they adopt a modern approach to a well-known subject. Following a brief introduction to the technology of microbial processes, the twelve most important application areas for microbial technology are described, from crude bulk chemicals to such highly refined biomolecules as enzymes and antibodies, to the use of microbes in the leaching of minerals and for the treatment of municipal and industrial waste. In line with their application-oriented topic, the authors focus on the "translation" of basic research into industrial processes and cite numerous successful examples. The result is a first-hand account of the state of the industry and the future potential for microbes in industrial processes. Interested students of biotechnology, bioengineering, microbiology and related disciplines will find this a highly useful and much consulted companion, while instructors can use the case studies and examples to add value to their teaching.

מידע נוסף

מידע נוסף
עמודים	424
פורמט	Paperback / softback
ISBN10	3527340351
יצא לאור ב	Weinheim
תאריך יציאה לאור	13 בנוב׳ 2019
תוכן עניינים	HISTORICAL OVERVIEW AND FUTURE PERSPECTIVE Use of fermentation procedures prior to the discovery of microorganisms (Neolithic Era = New Stone Age until 1850) Investigation of microorganisms and beginning of industrial microbiology (1850 until 1940) Development of new products and processes: antibiotics and other biomolecules (after 1940) Genetic engineering as successful tool for industrial microorganisms (after 1980) Future perspectives: Synthetic microbiology BIOPROCESS ENGINEERING Introduction Non-structured models Oxygen transport Heat generating aerobic processes Product recovery Modeling and simulation of reactor behavior Scale-up FOOD Fermented foods Microorganisms and metabolism Yeast fermentations - Industrial application of Saccharomyces species Vinegar - Incomplete ethanol oxidation by acetic acid bacteria such as Gluconobacter oxidans Bacterial and mixed fermentations- Industrial application of lactic acid bacteria, with or without yeast or molds Fungi as food Conclusions and outlook INDUSTRIAL ALCOHOLS AND KETONES Introduction Ethanol synthesis by Saccharomyces cerevisiae and Clostridium autoethanogenum 1,3-Propanediol synthesis by Escherichia coli Butanol and isobutanol synthesis by clostridia and yeast Acetone synthesis by solventogenic clostridia Outlook ORGANIC ACIDS Introduction Citric acid Lactic acid Gluconic acid Succinic acid Itaconic acid Downstream options for organic acids Perspectives AMINO ACIDS Introduction Production of amino acids L-Glutamate synthesis by Corynebacterium glutamicum L-Lysine L-Threonine synthesis by Escherichia coli L-Phenylalanine Outlook VITAMINS, NUCLEOTIDES, CAROTENOIDS Application and economic impact L-Ascorbic acid (vitamin C) Riboflavin (vitamin B2) Cobalamin (vitamin B12) Purine nucleotides ss-Carotene Perspectives ANTIBIOTICS AND PHARMACOLOGICALLY ACTIVE COMPOUNDS Microbial substances active against infectious disease agents or affecting human cells beta-Lactams Lipopeptides Macrolides Tetracyclines Aminoglycosides Claviceps alkaloids Perspectives PHARMACEUTICAL PROTEINS History, main areas of application and economic importance Industrial expression systems, cultivation and protein isolation and legal framework Insulins Somatropin Interferons - Application and manufacturing Human granulocyte colony-stimulating factor Vaccines Antibody fragments Enzymes Peptides View - Future economic importance ENZYMES Fields of application and economic impacts Enzyme discovery and improvement Production process for bacterial or fungal enzymes Polysaccharide-hydrolyzing enzymes Enzymes used as cleaning agents Feed supplements - phytases Enzymes for chemical and pharmaceutical industry Enzymes as highly selective tools for research and diagnostics Perspectives MICROBIAL POLYSACCHARIDES Introduction Heteropolysaccharides Homopolysaccharides Perspectives STEROIDS Fields of applications and economic importance Advantages of biotransformations during production of steroids Development of production strains and production processes Applied types of biotransformation Synthesis of steroids in organic-aqueous biphasic systems Side chain degradation at phytosterols by Mycobacterium to gain steroid intermediates Biotransformation of cholesterol to gain key steroid intermediates 11-Hydroxylation by fungi during synthesis of corticosteroids delta1-dehydrogenation by Arthrobacter for the production of prednisolone 17-keto reduction by Saccharomyces in testosterone production Double bond isomerization of steroids Perspectives BIOLEACHING Mineral-oxidizing acidophilic bacteria dissolve metals from sulfide ores Bioleaching of copper, nickel, zinc and cobalt Gold Uranium Perspectives WASTEWATER TREATMENT PROCESSES Introduction Biological treatments for carbon, nitrogen and phosphorus removal Wastewater treatment processes Advanced wastewater treatment Future perspectives
זמן אספקה	21 ימי עסקים